Authors retract study that raised questions about drug used to treat COVID-19

  
Via:  It Is ME  •  4 months ago  •  37 comments

By:   Karen Weintraub, USA TODAY 9 hrs ago

Authors retract study that raised questions about drug used to treat COVID-19
Authors of a major study on the drug hydroxychloroquine have asked the scientific journal The Lancet to retract their study, saying they are no longer confident in its findings.

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The study, initially published on May 22, raised questions about treating severely ill patients with the drug typically used against autoimmune diseases and malaria. Publication of the study, which found no benefit from the drug but potentially serious cardiac side effects, led other researchers, including the World Health Organization to halt studies of the drug. 

President Trump has touted hydroxychloroquine as a "game-changer" in the fight against COVID-19, and had taken it himself for a time, he said, hoping to prevent infection with the viral disease. 

Three authors of The Lancet study, Drs. Mandeep Mehra, Frank Ruschitzka and Amit  Patel, all prominent cardiologists, released a statement Thursday afternoon explaining their decision to ask for a retraction – a relatively rare step in science that is considered extremely embarrassing.
They opted for the retraction, they said, because outside reviewers could not confirm their results.

Although serious concerns were raised about the accuracy of the patient data they relied on in their study, the company that collected the information, Surgisphere Corporation, refused to release it for further analysis citing patient privacy.

"As such, our reviewers were not able to conduct an independent and private peer review and therefore notified us of their withdrawal from the peer-review process," the authors wrote in their retraction request. "Based on this development, we can no longer vouch for the veracity of the primary data sources."

The same authors also retracted a paper they had published in the New England Journal of Medicine last month based on the same data. In that paper, the researchers found they could not confirm earlier concerns about using heart disease and high blood pressure medications, called ACE inhibitors and ARBs, to treat hospitalized patients with COVID-19.

Other scientists praised the authors' decision to withdraw the papers, but said it was an example of the type of sloppy research published in the rush to combat the global pandemic.

There is a "glut of low quality science that is being performed in the wake of COVID19," said Vinay Prasad, an associate professor at the University of California San Francisco, and a frequent critic of scientific research.

"This paper might just be tip of the iceberg of potentially erroneous conclusions being drawn from studies fundamentally ill-suited to the task at hand," he continued via email. "If someone were keeping a book of 'Things to do better in a future pandemic' it probably already has 1,000 pages."

Others agreed.


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It Is ME
1  seeder  It Is ME    4 months ago

Well, ain't this a "Kick-in-the-ass" for Trump Haters !

800

Sloppy research published in the rush to combat PRESIDENT TRUMP ! jrSmiley_32_smiley_image.gif

 
 
 
The Magic Eight Ball
1.1  The Magic Eight Ball  replied to  It Is ME @1    4 months ago

once again we see a simple fact.

anything said by the left... go with the exact opposite and you will be correct more often than not.

 
 
 
It Is ME
1.1.1  seeder  It Is ME  replied to  The Magic Eight Ball @1.1    4 months ago
anything said by the left... go with the exact opposite and you will be correct more often than not.

So far, So Good. jrSmiley_79_smiley_image.gif

 
 
 
Tessylo
1.1.2  Tessylo  replied to  It Is ME @1.1.1    4 months ago
anything said by the 'right'... go with the exact opposite and you will be correct EVERY SINGLE TIME.  
 
 
 
MAGA
1.2  MAGA  replied to  It Is ME @1    4 months ago

I just wonder how many died needlessly because of all the opposition to the use of his medication was politically motivated because Trump mentioned it in a positive way early on.   

 
 
 
It Is ME
1.2.1  seeder  It Is ME  replied to  MAGA @1.2    4 months ago

I doubt we'll ever know !

 
 
 
Tessylo
1.2.2  Tessylo  replied to  MAGA @1.2    4 months ago

It's not a treatment for the Co-Vid 19 virus.  

No one died needlessly because they didn't get this drug.  

 
 
 
Ozzwald
1.3  Ozzwald  replied to  It Is ME @1    4 months ago
Well, ain't this a "Kick-in-the-ass" for Trump Haters !

Only if you don't bother reading the article, which apparently you didn't.

Why did they ask to retract the study?  

Surgisphere Corporation, refused to release it for further analysis citing patient privacy. "As such, our reviewers were not able to conduct an independent and private peer review and therefore notified us of their withdrawal from the peer-review process," the authors wrote in their retraction request.

Not because of anything showing the study as incorrect, but because privacy issues of the patients prevented peer review.  They wanted peer review before publishing the study.

I also notice that you completely ignored the other studies that showed the exact same results.

From YOUR SEEDED ARTICLE :

Other studies have also raised questions about using hydroxychloroquine against COVID-19, and the French study that first led to its widespread use against the disease has been roundly criticized as sloppy and misleading.  A study published Wednesday in the New England Journal of Medicine, for instance, found that the drug was not effective in preventing COVID-19, though other studies looking at that question continue.

Your entire seed is a....

shutterstock_344519003-796x565.jpg

 
 
 
It Is ME
1.3.1  seeder  It Is ME  replied to  Ozzwald @1.3    4 months ago

No Fail at all.

They did "Retract the Study" !

"Surgisphere Corporation, refused to release it for further analysis citing patient privacy. "As such, our reviewers were not able to conduct an independent and private peer review and therefore notified us of their withdrawal from the peer-review process," the authors wrote in their retraction request."

No Peer Review, study is just another piece of paper put out by Someone that "Says" something.

Did you MISS these parts:

The same authors also retracted a paper they had published in the New England Journal of Medicine last month based on the same data. 

"Based on this development, we can no longer vouch for the veracity of the primary data sources."

"There clearly was at least sloppiness, if not somehow misrepresentation of the data," said Philip Rosenthal, a professor of medicine at the University of California, San Francisco and a signatory, along with nearly 180 other scientists, to a letter sent last week raising questions about the study." 

Seems these ….. researchers have more problems than just someone else not "Providing" patient info. 

No Backup..... No viable study !

 
 
 
Tessylo
1.3.2  Tessylo  replied to  Ozzwald @1.3    4 months ago

What a surprise that he didn't even READ the article that he posted.  

 
 
 
Ozzwald
1.3.3  Ozzwald  replied to  It Is ME @1.3.1    4 months ago
Based on this development, we can no longer vouch for the veracity of the primary data sources.

The PRIMARY DATA SOURCES are the PATIENTS!!!  Patient privacy prevented peer reviews since they'd need to provide names and medical info for those patients.

You should have READ THE DAMNED ARTICLE BEFORE SEEDING AND CLAIMING FALSEHOODS!

 
 
 
Ozzwald
1.3.4  Ozzwald  replied to  Tessylo @1.3.2    4 months ago
What a surprise that he didn't even READ the article that he posted.

And he is going to spin himself into a knot trying to justify it.

 
 
 
It Is ME
1.3.5  seeder  It Is ME  replied to  Ozzwald @1.3.4    4 months ago
And he is going to spin himself into a knot trying to justify it.

The "Study" is Toast, as the article notes. No one will sign on to something "Sloppy" !

It's in the article.

What a "Twist" huh !

 
 
 
It Is ME
1.3.6  seeder  It Is ME  replied to  Ozzwald @1.3.3    4 months ago
You should have READ THE DAMNED ARTICLE BEFORE SEEDING AND CLAIMING FALSEHOODS!

You should try and understand what the article actually says. No backup data to show, It's all Hogwash ! 

"The Lancet to retract their study, saying they are no longer confident in its findings."

 
 
 
Ozzwald
1.3.7  Ozzwald  replied to  It Is ME @1.3.6    4 months ago
You should try and understand what the article actually says. No backup data to show, It's all Hogwash You would sound less silly if you would READ and UNDERSTAND the articles, BEFORE you seed them.  Now you are trying to dig and find something, anything, to back up your blatantly false claims. 

It clearly states in the article that they are retracting it due to patient privacy, eliminating their ability to provide peer review.

Perhaps, as your comeback, you should provide articles showing studies, that SUPPORT Hydroxychloroquine as being effective in treating or preventing Coronavirus.

Come on, I dare you, provide a link, to a study, that supports hydroxychloroquine.  Back up your claim for once.

 
 
 
It Is ME
1.3.8  seeder  It Is ME  replied to  Ozzwald @1.3.7    4 months ago
Perhaps, as your comeback, you should provide articles showing studies, that SUPPORT Hydroxychloroquine as being effective in treating or preventing Coronavirus.

Gosh ….. just perhaps.....That's NOT what this article is about.....hmmmmmm. jrSmiley_88_smiley_image.gif

Oh..... I know....maybe....just maybe, you could "Seed" your own article. jrSmiley_97_smiley_image.gif

 
 
 
Ozzwald
1.3.9  Ozzwald  replied to  It Is ME @1.3.8    4 months ago
Gosh ….. just perhaps.....That's NOT what this article is about.....hmmmmmm

This article is not about Hydroxychloroquine?????

67318920.jpg

 
 
 
Split Personality
1.3.10  Split Personality  replied to  It Is ME @1.3.1    4 months ago
Seems these ….. researchers have more problems than just someone else not "Providing" patient info.  No Backup..... No viable study

The three researchers in question were fluffing their own resumes by getting "professionally" published for analyzing someone else's data collections.

Their conclusion might be correct, but the fact that Surgisphere won't co-operate demands retraction of the two papers.

In medical research it is referred to as integrity.

Seems like they would have had more integrity by using 100% verifiable data, but they jumped the shark and now their reputations are besmirched.

 
 
 
Nerm_L
2  Nerm_L    4 months ago

Politics is putting our health at risk.  Why can't we regulate THAT health threat?

Instead of face masks, maybe we can demand politicians wear muzzles.  At the very least there should be warning labels.

SURGEON GENERAL’S WARNING: Quitting Politics Now Greatly Reduces Serious Risks to Your Health.

 
 
 
It Is ME
2.1  seeder  It Is ME  replied to  Nerm_L @2    4 months ago

These last few years have been a total hoax …. perpetrated by so-called "Experts" in one Field or another.

HATE TRUMP ...… has made many...… VERY SLOPPY.... Just to get their "Name" out there !

I hear that touching "Hard Surfaces" really isn't "Instant infection" anymore. 

 
 
 
Tessylo
2.1.1  Tessylo  replied to  It Is ME @2.1    4 months ago

These last few years with this 'president' certainly has been a hoax, a sham, foisted on us decent folks.  

 
 
 
Nerm_L
2.1.2  Nerm_L  replied to  It Is ME @2.1    4 months ago
These last few years have been a total hoax …. perpetrated by so-called "Experts" in one Field or another.

Well, I don't agree with 'hoax'.  The last few years have been a meme.

256

 
 
 
It Is ME
2.1.3  seeder  It Is ME  replied to  Nerm_L @2.1.2    4 months ago

LOL !

That fits !

 
 
 
MAGA
2.1.4  MAGA  replied to  Tessylo @2.1.1    4 months ago

You must have really hated today’s economic news then...

 
 
 
cjcold
2.2  cjcold  replied to  Nerm_L @2    4 months ago

And you would replace politics and the rule of law with...…….?

 
 
 
Nerm_L
2.2.1  Nerm_L  replied to  cjcold @2.2    4 months ago
And you would replace politics and the rule of law with...…….?

Perhaps we need to replace politics with the rule of law.

Politicians on both sides of the aisle have been ignoring laws they don't like.  The last four years kinda shows that politics isn't really that compatible with the rule of law.

 
 
 
cjcold
2.2.2  cjcold  replied to  Nerm_L @2.2.1    4 months ago

Absolute power corrupts absolutely. 

Perhaps we should start there.

 
 
 
Nerm_L
2.2.3  Nerm_L  replied to  cjcold @2.2.2    4 months ago
Absolute power corrupts absolutely. 

There's a meme for that.

256

 
 
 
Tessylo
3  Tessylo    4 months ago

No trolling.

TRUTH

 
 
 
It Is ME
3.1  seeder  It Is ME  replied to  Tessylo @3    4 months ago
TRUTH

Do you have any Backup ?

 
 
 
Tessylo
3.1.1  Tessylo  replied to  It Is ME @3.1    4 months ago
Do you have any Backup ?

 
 
 
It Is ME
3.1.2  seeder  It Is ME  replied to  Tessylo @3.1.1    4 months ago
Do you have any Backup ?

Read the seeded article you're commenting on....

and.....

just for giggles...… Comment #1.1.3.

[deleted]

 
 
 
Tessylo
3.1.3  Tessylo  replied to  It Is ME @3.1.2    4 months ago

Yes, more than the backs of cereal boxes like some.  

 
 
 
It Is ME
3.1.4  seeder  It Is ME  replied to  Tessylo @3.1.3    4 months ago
Yes, more than the backs of cereal boxes like some. 

That's a good thing. jrSmiley_15_smiley_image.gif

Now....

What do the "Article and comment" I pointed you to, note as to the proof you asked for ? jrSmiley_87_smiley_image.gif

 
 
 
Tessylo
4  Tessylo    4 months ago

I'm still unsure of what you are trying to 'prove' with this article which doesn't 'prove' anything.  

 
 
 
Nerm_L
4.1  Nerm_L  replied to  Tessylo @4    4 months ago
I'm still unsure of what you are trying to 'prove' with this article which doesn't 'prove' anything. 

The article provides 'proof' that international policy decisions were guided by 'alternative facts'.  The policy concerning hydroxychloroquine was guided by the same sort of proof as WMD in Iraq.

Hydroxychloroquine is generic drug that can be produced quickly and made widely available to poorer countries at low cost.  The political uproar over hydroxychloroquine (because of the bad orange man) denies a possible treatment to poorer countries for political reasons.  

COVID-19 isn't limited to rich countries that can afford expensive treatments.

 
 
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