These dogs are getting a cancer vaccine. If it works, humans could be next

  
Via:  Jasper2529  •  9 months ago  •  38 comments


These dogs are getting a cancer vaccine. If it works, humans could be next
"Cancer is actually the leading cause of death in adult dogs," Thamm says. "They develop these tumors spontaneously as a result of old age in a way that's very, very similar to the way humans do."

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Cancer: Research, Survivors, Friends

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If you ask most experts in the   cancer   community, creating a wide-ranging   vaccine   that prevents tumors like we prevent infectious diseases is damn near impossible.



The idea may be tantalizing, but study after study over the past several decades has taught doctors that cancer is personal. Everyone's looks different on a molecular level. And each tumor is an agile, devious adversary that mutates as it grows to outwit the human immune system.

"They may be right," Stephen Johnston says, but "if the chance is 10% that it might work, I can't see any reason why we shouldn't take that chance."

Johnston isn't an oncologist. He's a scientist, inventor and director of Arizona State University's Center for Innovations in Medicine. He recently launched a clinical trial to test a cancer vaccine in hundreds of dogs across the country. The trial will examine whether the vaccine delays or prevents a variety of cancers in healthy, older dogs. If it's successful, Johnston says, it could lay the groundwork for developing a similar vaccine for humans.





Many canine cancers are also similar to human cancers on a molecular level. This has a lot to do with our shared environments, Thamm explains -- we breathe the same air, drink the same water, run on lawns sprayed with the same chemicals. Thamm told Johnston dogs are also ideal for a study like this because they don't live as long as humans, so researchers will be able to see whether the vaccine works in three to five years instead of 10 to 30.


So Thamm and Johnston decided to undertake what they say is the largest interventional clinical trial ever in canines. It's called the   Vaccination Against Canine Cancer Study .



Full article and video here .


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Jasper2529
1  seeder  Jasper2529    9 months ago
Thamm emphasizes that they are not inducing cancer in the dogs participating in the trial; the dogs will be given the vaccine and then followed in their normal environments for the next several years.
"Owners have really been overwhelmingly positive about the idea behind this trial. They, of course, loved the idea that they have the potential to participate in research that might help other dogs, and even people in the future."
 
 
 
Jasper2529
2  seeder  Jasper2529    9 months ago
Even if the vaccine works in dogs, the team has a long road ahead to get approval for a human clinical trial. Animal testing is often unpredictable, and the vast majority of drugs tested in animals are never approved by the FDA for use in humans because they are deemed unsafe or ineffective.
 
 
 
Jasper2529
3  seeder  Jasper2529    9 months ago
Vaccines teach the immune system to recognize dangerous invaders quickly and fight back. The same way an athlete develops muscle memory during training, vaccines help your immune system develop memory cells so antibodies can respond better and faster to antigens (any foreign cell or substance that triggers an immune response).
In other words, vaccines prepare your body so that in the case of war -- your body vs. XYZ infection -- your body wins.
 
 
 
Perrie Halpern R.A.
3.1  Perrie Halpern R.A.  replied to  Jasper2529 @3    9 months ago

Great find Jasper. This would be an amazing study and think of the number of lives it could save both human and K9. Let's hope that they really make some headway. 

 
 
 
CB
4  CB     9 months ago
And each tumor is an agile, devious adversary that mutates as it grows to outwit the human immune system.

"Devious." That makes it fearsome. Something that appears to have a life (of a sort) all its own! That means it strikes back in order to live!

 
 
 
charger 383
5  charger 383    9 months ago

Be great if this works for dogs and people

 
 
 
Kavika
6  Kavika     9 months ago

We lost our Annie to mass cell tumors in 2018. The University of Missouri school of Veterinary Medicine in Columbia did everything that they could but the cancer was relentless and finally took my sweet girls life. 

We are going through the same thing currently. Our mini Doxie, Wiki Warrior Wonder Wiener, she had a tumor removed from her neck earlier this week. We'll know sometime next week if it was malignant. Hoping for the best. 

The operation was done at the University of Florida school of Veterinary Medicine in Gainesville. 

Thanks for the article as close family members are fighting various forms of cancer currently.

Hoping that the vaccine is successful in the dogs and than with humans.

 
 
 
Buzz of the Orient
6.1  Buzz of the Orient  replied to  Kavika @6    9 months ago

Wishing Wiki Wellness!!!

 
 
 
Kavika
6.1.1  Kavika   replied to  Buzz of the Orient @6.1    9 months ago

Thanks Buzz.

 
 
 
charger 383
6.2  charger 383  replied to  Kavika @6    9 months ago

Good wishes for Wiki 

Charger, Bo the Doberman and Bailey the puppy 

 
 
 
Kavika
6.2.1  Kavika   replied to  charger 383 @6.2    9 months ago

Thanks Charger.

 
 
 
sandy-2021492
6.3  sandy-2021492  replied to  Kavika @6    9 months ago

Best wishes to Wiki, you, and Red.

 
 
 
Kavika
6.3.1  Kavika   replied to  sandy-2021492 @6.3    9 months ago

Thanks Sandy.

 
 
 
pat wilson
6.3.2  pat wilson  replied to  Kavika @6.3.1    9 months ago

Same here Kavika, I know what Wiki means to you.

 
 
 
Kavika
6.3.3  Kavika   replied to  pat wilson @6.3.2    9 months ago

Thanks Pat.

 
 
 
dave-2693993
6.4  dave-2693993  replied to  Kavika @6    9 months ago

Kavika, distressing news.

Best wishes for wiki and family.

Lost my mom, going on 11 years ago and dad fighting melanoma for the past year.

Best to you and family.

 
 
 
Kavika
6.4.1  Kavika   replied to  dave-2693993 @6.4    9 months ago

Thanks dave, 

The best to your dad.

 
 
 
Raven Wing
6.4.2  Raven Wing  replied to  dave-2693993 @6.4    9 months ago

Prayers for your Father, Dave. 

 
 
 
Raven Wing
6.5  Raven Wing  replied to  Kavika @6    9 months ago

I am so sorry to hear about Wiki's tumor removal, Kavika. I will keep Wiki in my prayers that it is not cancerous. I know how much she means to you and Red. But, Wiki is a fighter, and hopefully, the update news will be good news.

 
 
 
Kavika
6.5.1  Kavika   replied to  Raven Wing @6.5    9 months ago

Thanks RW

 
 
 
CB
6.6  CB   replied to  Kavika @6    9 months ago

Kavika, I wish you much peace of mind in these circumstances. 2018 and now this in 2019.  And human family cancer battles as well. You plate is filling up! Be strong and remember to take your vitamins—you have a lot to think on.

 
 
 
MrFrost
6.7  MrFrost  replied to  Kavika @6    9 months ago
Wiki Warrior Wonder Wiener

I am ashamed to admit I chuckled at the name, given what she is going through. All the best wishes and positive energy I can send. 

Patrick, Kit-Kat and Amy Kitten, (AK). 

 
 
 
Kathleen
7  Kathleen    9 months ago

I wish Wiki well...

It would be wonderful to have a vaccine for cancer.

 
 
 
Kavika
7.1  Kavika   replied to  Kathleen @7    9 months ago

Thanks Kathleen.

 
 
 
Perrie Halpern R.A.
7.1.1  Perrie Halpern R.A.  replied to  Kavika @7.1    9 months ago

Best wishes for Wiki. Fingers crossed that she will be AOK. 

 
 
 
Kavika
7.1.2  Kavika   replied to  Perrie Halpern R.A. @7.1.1    9 months ago

Thanks Perrie.

 
 
 
dave-2693993
8  dave-2693993    9 months ago

Wow, extreme odds. If someone can go for it, then go for it.

 
 
 
Enoch
9  Enoch    9 months ago

Dear Friend Jasper: This is an important topic, and article on it.

Thanks for posting.

Please keep us posted.

P&AB.

Enoch.

 
 
 
KatPen
10  KatPen    9 months ago

Best wishes for good news for Wiki!  Pets and hugs.

 
 
 
Kavika
10.1  Kavika   replied to  KatPen @10    9 months ago

Thanks Kat.

 
 
 
CB
11  CB     9 months ago

I just realized this is about a vaccine for cancer. Wow! Tall order. Great effort to undertake all the same. We need more 'tools.' They seem to be 'attacking' cancer in many diverse ways!

 
 
 
The Magic Eight Ball
12  The Magic Eight Ball    9 months ago

this is awesome... I hope it works,

with luck it will be fit for man and beast. and cats.

cheers :)

 

 
 
 
CB
12.1  CB   replied to  The Magic Eight Ball @12    9 months ago

Goodness, I hope it works! A vaccine for cancer. The science community is working hard at tackling cancer on the field of play! Bravo for every team effort and each small and large success accomplished!

 
 
 
MrFrost
12.2  MrFrost  replied to  The Magic Eight Ball @12    9 months ago
and cats.

Having just lost a cat to cancer last week, I totally agree. 

 
 
 
CB
12.2.1  CB   replied to  MrFrost @12.2    9 months ago

I saw your article on your amazing animal friend last week. I remember how you stated you had to help it with its "messes." I have a friend who lost a good friend dog to cancer and I remember going over to see him washing his dog's behind after an uncontrollable "movement." I thought such devotion. Of course, it died and my friend took care of the matter appropriately.

If I did not write at the time-more than some votes last week on the comments from others, then I want to do so now: I am wishing you and all animal lovers the best in vaccines in the future. Here's a toast to the professionals who are trying to take a big chunk out of cancer!

 
 
 
MrFrost
14  MrFrost    9 months ago

Excellent article Jasper, thanks for this. 

 
 
 
Sunshine
15  Sunshine    9 months ago

Interesting...Thanks Jasper.

Cancer seems to be touching everyone's life in one way or another lately.  Seeing an animal suffer is extremely heartbreaking.  

My mother lost her dog to cancer a few years ago and my neighbor just lost theirs.  

 
 
 
Jasper2529
16  seeder  Jasper2529    9 months ago

To everyone - Thank you for your comments.

To those who have lost beloved family members and/or pets to this insidious disease called cancer: I share your optimism that this vaccine trial helps us find a cure!

 
 
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