First Native American woman to travel to space
Astronaut Nicole Aunapu Mann, of the Wailacki of the Round Valley Indian Tribes, will be mission commander - responsible for all phases of flight.
She will go to the International Space Station on 29 September, Nasa says.
"It's very exciting," she told newspaper Indian Country Today.
"I think it's important that we communicate this to our community, so that other Native kids... realise that some of those barriers that used to be there are really starting to get broken down," she added.
Ms Mann says that in her allocated 3.3 lb (1.4kg) for personal items she will take "a dreamcatcher that my mother gave me when I was very young".
According to the Indigenous Foundation,dreamcatchers symbolise unityand provide protection.
Ms Mann will be with three colleagues on the SpaceX Dragon spacecraft as part of the Crew-5 mission.
She could also go to the Moon. In 2020 she was selected to be in apool of astronautseligible for Nasa's Artemis programme that will send humans to the Moon.
Ms Mann, originally from California, studied mechanical engineering at Stanford university.
She become a colonel in the Marine Corps, flying various fighter aircraft. She has been deployed twice on aircraft carriers supporting combat operations in Iraq and Afghanistan, and was awarded six medals for her service to the US military.
This expedition will be Mann's first spaceflight since she became an astronaut in 2013, Nasa confirms.
She is one of eight members of the 21st Nasa astronaut class, formed for space station operations and potential future assignments to the Moon and Mars.
She will be joined byastronaut and pilot Josh Cassada, astronaut Koichi Wakata from the Japan Aerospace Exploration Agency, and Russian cosmonaut Anna Kikina.
This is the fifth rotational mission to the International Space Station where the team will conduct 250 scientific experiments which Nasa says willhelp benefit life on Earthand prepare for human exploration beyond the planet.
In 2002, John Herrington, an enrolled member of the Chickasaw Nation, was the first Native American man to fly into space. He carried the Nation's flag and a traditional flute on his 13-day voyage.
Just luv seeing these advancements
Ayiih, a true ogichidaa.
Congratulations Col. Mann.
Good for her, the more Native Americans get publicity in media for these kind of achievements, the more they will be seen as an integral part of American society and culture.
American Indians have never gotten enough media attention but it seems in the last couple years that may be slowly changing.
COL Aunapu-Mann, an athlete, scholar, warrior and now an astronaut. Amazing achievements.
What wonderful news! She is a wonderful example to Indian children everywhere, that their dreams can go to the heavens. I wish her great success and the spirits of our ancestors go with her.
Morning...good on her..
Leading the way so others will follow in her footsteps...
The Round Valley Tribe is made up of a confederation of smaller tribes.
Today, the Yuki are federally recognized along with the Wailacki, Nomlacki, Pitriver, Concow, and Pomo in a confederation respectively known as Round Valley ...
NASA has quite a number of Native Americans working with them -
She is very impressive. I think we can expect many more outstanding achievements from her in the future.
I hope that she will write or speak of her experience in space, because it would be edifying to learn of that experience through the eyes of a Native American.