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Vitamin D Determines Severity in COVID-19: Researchers Urge Government to Change Advice

  
Via:  Nerm_L  •  4 years ago  •  13 comments

By:   Trinity College Dublin (SciTechDaily)

Vitamin D Determines Severity in COVID-19: Researchers Urge Government to Change Advice
Here we see observational evidence of a link of vitamin D with mortality. Optimizing vitamin D intake to public health guidelines will certainly have benefits for overall health and support immune function.

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The next obvious golden opportunity for profiteers.  Undoubtedly someone will begin hoarding vitamin D.

Skin is more than just a container that holds the icky stuff inside.  Skin is an organ that produces vitamin D along with many other functions that contributes to health.  What would be interesting is a study that correlates susceptibility with a more outdoor lifestyle.  Are agrarian lifestyles less susceptible to severity of COVID-19?

Hiding in our hovels may be making us more susceptible to the severity of COVID-19.


S E E D E D   C O N T E N T



Researchers from Trinity College Dublin are calling on the government in Ireland to change recommendations for vitamin D supplements.

A new publication from Dr. Eamon Laird and Professor Rose Anne Kenny, School of Medicine, and the Irish Longitudinal Study on Ageing (TILDA), in collaboration with Professor Jon Rhodes at University of Liverpool, highlights the association between vitamin D levels and mortality from COVID-19.

The authors of the article, just published in the Irish Medical Journal, analyzed all European adult population studies, completed since 1999, which measured vitamin D and compared vitamin D and death rates from COVID-19.

Vitamin D is produced in the skin from UVB sunlight exposure and is transported to the liver and then the kidney where it is changed into an active hormone that increases calcium transport from food in the gut and ensures calcium is adequate to keep the skeleton strong and free of osteoporosis.

But vitamin D can also support the immune system through a number of immune pathways involved in fighting SARS-CoV-2. Many recent studies confirm the pivotal role of vitamin D in viral infections.

This study shows that, counter intuitively, countries at lower latitude and typically sunny countries, such as Spain and Northern Italy, had low concentrations of vitamin D and high rates of vitamin D deficiency. These countries also experienced the highest infection and death rates in Europe.

The northern latitude countries of Norway, Finland, and Sweden, have higher vitamin D levels despite less UVB sunlight exposure, because supplementation and fortification of foods is more common. These Nordic countries have lower COVID-19 infection and death rates. The correlation between low vitamin D levels and death from COVID-19 is statistically significant.

The authors propose that, whereas optimizing vitamin D levels will certainly benefit bone and muscle health, the data suggests that it is also likely to reduce serious COVID-19 complications. This may be because vitamin D is important in regulation and suppression of the inflammatory cytokine response, which causes the severe consequences of COVID-19 and 'acute respiratory distress syndrome' associated with ventilation and death.

Professor Rose Anne Kenny said:

"In England, Scotland and Wales, public health bodies have revised recommendations since the COVID-19 outbreak. Recommendations now state that all adults should take at least 400 IU vitamin D daily. Whereas there are currently no results from randomized controlled trials to conclusively prove that vitamin D beneficially affects COVID-19 outcomes, there is strong circumstantial evidence of associations between vitamin D and the severity of COVID-19 responses, including death."

"This study further confirms this association. We call on the Irish government to update guidelines as a matter of urgency and encourage all adults to take supplements during the COVID-19 crisis. Deficiency is frequent in Ireland. Deficiency is most prevalent with age, obesity, in men, in ethnic minorities, in people with diabetes, hypertension and in nursing homes."

Dr. Eamon Laird added:

"Here we see observational evidence of a link of vitamin D with mortality. Optimizing vitamin D intake to public health guidelines will certainly have benefits for overall health and support immune function. Research like this is still exploratory and we need further trials to have concrete evidence on the level of vitamin D that is needed for optimal immune function. However, studies like this also remind us how low our vitamin D status is in the population (even in sunny countries) and adds further weight to some sort of mandatory vitamin D fortification policy. If the Nordic countries are allowed to do this, there is no reason Ireland, the UK or rest of Europe can't either."

Reference: "Vitamin D and Inflammation: Potential Implications for Severity of Covid-19" by E. Laird, J. Rhodes and R.A. Kenny, 11 May 2020, Irish Medical Journal.
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Nerm_L
Professor Expert
1  seeder  Nerm_L    4 years ago

The seeded article contains a link that provides a little more detail.

Vitamin D Linked to Low Coronavirus Death Rate - SciTechDaily

The importance of research on vitamins shouldn't be dismissed just because it's not the latest sexy science.

 
 
 
Just Jim NC TttH
Professor Principal
1.1  Just Jim NC TttH  replied to  Nerm_L @1    4 years ago

Heard some rumblings early on about D. I've been taking 2000 units of vitamin D a day for a month now..........just in case

 
 
 
Nerm_L
Professor Expert
1.1.1  seeder  Nerm_L  replied to  Just Jim NC TttH @1.1    4 years ago
Heard some rumblings early on about D. I've been taking 2000 units of vitamin D a day for a month now..........just in case

Well, my experience with vitamin supplements is they do provide benefit.  I don't eat that much (usually one small meal a day) so I worry about vitamin deficiency.  But keep in mind that more isn't necessarily better.  

What is vitamin D toxicity? Should I be worried about taking supplements? - Mayo Clinic

Typically it's necessary to intake outrageous amounts of vitamins before toxicity begins to appear.  However, that toxic response is usually the result of overwhelming the body's ability to eliminate the excess.  Larger doses doesn't necessarily mean greater benefit; you'll end up pissing most of it away.

 
 
 
Just Jim NC TttH
Professor Principal
1.1.2  Just Jim NC TttH  replied to  Nerm_L @1.1.1    4 years ago

I realize that. The owner of our company is a health freak and he gets advice from a "doctor" that published a "How to Get Over the Flu" in which he states at the onset to start taking 2000 units of vitamin C every six minutes, yes SIX minutes, until you feel the symptoms start to subside. That's 200000 an hour. Due to that, I looked up the toxicity of C. It wasn't pretty much like you stated above.

Thanks for the response.

 
 
 
Baron Creek
Junior Quiet
3  Baron Creek    4 years ago

Match your Vitamin D and raise you one nicotine patch .

 
 
 
Nerm_L
Professor Expert
3.1  seeder  Nerm_L  replied to  Baron Creek @3    4 years ago
Match your Vitamin D and raise you one nicotine patch .

Seeds and stems are all that's left.

 
 
 
Sparty On
Professor Principal
3.1.1  Sparty On  replied to  Nerm_L @3.1    4 years ago

No stems no seeds that you don’t need ...... Acapulco gold is ..... bad ass weed ....

 
 
 
It Is ME
Masters Guide
4  It Is ME    4 years ago

I'm an "Outsider" jrSmiley_15_smiley_image.gif , and take my "Over 50" Vitamins everyday, just like the "Doc". told me to. jrSmiley_20_smiley_image.gif

 
 

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