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Herd immunity works—if you don’t care how many people die

  

Category:  News & Politics

Via:  tessylo  •  4 years ago  •  36 comments

By:   BY LAURIE GARRETT AND JOHN MOORE July 27, 2020 2:00 PM EDT

Herd immunity works—if you don’t care how many people die

S E E D E D   C O N T E N T



Herd immunity works—if you don’t care how many people die



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 AND 

July 27, 2020   2:00 PM EDT

The herd immunity coronavirus strategy predictably failed in Sweden. Humans often defy the best interests of the herd, write Laurie Garrett and John Moore.

From Wall Street to Main Street, much hope in the COVID-19 crisis has been placed on “herd immunity,” the idea that a sufficient number of people will eventually develop antibodies to stop virus spread and curtail the pandemic. That thinking is behind President Donald Trump’s   insisting , “The virus will disappear. It will disappear.”

The   Swedish government   chose to pursue herd immunity during the spring when COVID-19 overwhelmed many European nations, favoring voluntary control measures over strict lockdown procedures. This week, 21 Swedish infectious diseases experts   denounced   the policy, writing, “In Sweden, the strategy has led to death, grief, and suffering, and on top of that there are no indications that the Swedish economy has fared better than in many other countries. At the moment, we have set an example for the rest of the world on how not to deal with a deadly infectious disease.”

The United Kingdom also   flirted with a herd immunity strategy   in March, but it soon backtracked as the   death toll rose   and Prime Minister Boris Johnson was hospitalized with COVID-19.


The problem with herd immunity  is the word “herd.” Some 400 vaccines are used on livestock, fish, pets, and zoo animals worldwide: all creatures without free will. A herd can be protected against a disease by allowing a pathogen to spread within it, killing some but leaving the survivors resistant to infection. The same outcome can be achieved, at less cost in lives, by vaccinating a sufficient percentage of the herd. In both scenarios, the percentage needing protection depends on the pathogen’s infectiousness.  For example , if 70% of domestic dogs are vaccinated against rabies, the worldwide canine herd is protected and dog bites do not transmit this lethal virus to humans.

In a democracy, humans have free will, including   the ability to choose   to do idiotic things that put themselves and others   at high risk for infection . They chafe at restriction, bridle at confinement, and often defy the best interests of the herd.

Modeling of SARS-CoV-2 indicates  that an infection rate of 65% to 70% is needed to protect the rest of our freewheeling human herd. Thus, two-thirds of the U.S. population must become resistant to the virus before our epidemic shifts from collective catastrophe to isolated incidents. But allowing infection of about 200 million Americans translates to more than 1 million deaths, a morally reprehensible toll. The 10% antibody-positive rate among Swedes, the  5% seen  in survivors of  Spain’s epidemic , and even the 45% found among London  health care workers  involved in COVID-19 patient care come nowhere near herd immunity levels. 

A   study   of blood samples collected this spring in 10 U.S. cities found the highest seropositivity rate, 22.7%, was in New York City at its March/April epidemic peak. The city’s   chief medical officer , Jay Varma, says, however, that this antibody rate offers no solace, since “herd immunity is a very unlikely explanation…We’re not nearly at a level where we would expect that immunity would play a major role in decreasing transmission.”

Moreover, a positive result on an antibody test does not guarantee protective immunity; the detected antibodies may be neither strong enough to counter the virus nor targeted appropriately. It seems paradoxical, but the strongest antibody responses   are seen   in the sickest patients, including those who die. People with asymptomatic or mild infections usually develop weak responses. 

The common perception that someone who recovered quickly had strong antibodies that “beat the virus” is flawed. It’s unknown whether the weaker antibody responses are protective against reinfection, and we’re still foggy on how   T cell immunity   kicks in. Isolated cases are increasingly   reported   of   individuals   who survived COVID-19, tested negative for the virus, and then weeks later were reinfected and took ill. These   cases are rare   but may become more common.

The key issue is   duration : How long does immunity to SARS-CoV-2 last? We are still very early in this pandemic. No studies have tracked immune responses in people for much longer than three months. Results are mixed. In New York City,   local researchers say   people seem to still be robustly immune after three months. But a   London study   saw immunity waning strongly over that period, and in the Chinese district of Wanzhou, 40% of asymptomatically infected people and 12.9% of COVID-19 cases   rapidly became antibody-negative .

Such findings should come as no surprise. Immunity to the related coronaviruses that cause common colds wanes  after about a  year , so people can catch colds over and over again. Nobody discusses herd immunity for common cold viruses—because there is no such thing.

If herd immunity via infections is off the table, the world needs a vaccine. Several Operation Warp Speed (a public-private program designed to speed up COVID-19 vaccine development and distribution) vaccine candidates have elicited antibodies and T cells in human trials, but it’s too early to tell whether any will protect against infection or reduce the severity of disease. Only large-scale efficacy trials can provide those much-needed answers. However, the urgency of the pandemic and other pressures will probably mean that vaccines will be approved for mass use well before we know their duration of protection. Nobody wants to wait a full year to see if immunity is sustained for 70% of the human herd.

It is quite foreseeable that immunity to the first approved COVID-19 vaccines will diminish over time, requiring frequent booster injections.

Of course, a vaccine can only confer herd immunity if it is widely used. Opinion   surveys   show many American “herd” members have already decided to reject a SARS-CoV-2 vaccine.   Polling results in May   found only 49% would take it, and 31% were unsure, while 20% would refuse a vaccine under any circumstances. A July   survey   found similarly sobering results. A scientific task force   has warned   that the Operation Warp Speed vaccine effort “rests upon the compelling yet unfounded presupposition that ‘if we build it, they will come.’”

To boost public confidence, it is essential that vaccines are approved only after both efficacy and safety are rigorously proved. Any   rushed political interventions and election year politics   that compromise safety assessments could render mass immunization impossible by further fostering public distrust.

As prominent economists have  put it , “Absolute economic recovery rests on the eradication of COVID-19. The reality is that the timeline, efficacy, cost, and distribution of a vaccine all introduce factors that we do not believe are appropriately reflected in the markets and public sentiment.” 

This killer coronavirus will not simply “disappear” as long as human behavior allows it to spread within   the herd . A   Wall Street miracle , where powerful, lasting immunity emerges   en masse and allows the   world economy   to return to its 2019 ways, is delusional. Until a vaccine or multiple vaccines are developed   and used   on a global scale to confer herd immunity, human beings must exercise free will to protect themselves and the rest of the human herd by using masks, social distancing, and good old-fashioned common sense.

Laurie Garrett is a Pulitzer Prize–winning science writer, author of   Betrayal of Trust: The Collapse of Global Public Health   and other books, and a science




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Tessylo
Professor Principal
1  seeder  Tessylo    4 years ago

The    Swedish government    chose to pursue herd immunity during the spring when COVID-19 overwhelmed many European nations, favoring voluntary control measures over strict lockdown procedures. This week, 21 Swedish infectious diseases experts    denounced    the policy, writing, “In Sweden, the strategy has led to death, grief, and suffering, and on top of that there are no indications that the Swedish economy has fared better than in many other countries. At the moment, we have set an example for the rest of the world on how not to deal with a deadly infectious disease.”

 
 
 
Tessylo
Professor Principal
2  seeder  Tessylo    4 years ago

Modeling of SARS-CoV-2  indicates   that an infection rate of 65% to 70% is needed to protect the rest of our freewheeling human herd. Thus, two-thirds of the U.S. population must become resistant to the virus before our epidemic shifts from collective catastrophe to isolated incidents. But allowing infection of about 200 million Americans translates to more than 1 million deaths, a morally reprehensible toll. The 10% antibody-positive rate among Swedes, the   5% seen   in survivors of   Spain’s epidemic  , and even the 45% found among London   health care workers   involved in COVID-19 patient care come nowhere near herd immunity levels. 

 
 
 
Sean Treacy
Professor Principal
3  Sean Treacy    4 years ago

This is an outdated article with outdated thinking. 

New models show immunity can be achieved at 43% within communities and reductions in transmission At 20%.  New York City has almost certainly achieved limited herd immunity as have other hard hit places like  northern Italy, wuhan and the slums of Mumbai.

 
 
 
bbl-1
Professor Quiet
3.1  bbl-1  replied to  Sean Treacy @3    4 years ago

Wouldn't put to much faith in Bannon's or Putin's models.

 
 
 
Sean Treacy
Professor Principal
3.1.1  Sean Treacy  replied to  bbl-1 @3.1    4 years ago

So you are of the New York  times is a front for Putin camp..

good to let everyone know that upfront.

 
 
 
bbl-1
Professor Quiet
3.1.2  bbl-1  replied to  Sean Treacy @3.1.1    4 years ago

No.  A legitimate newspaper prints the story.  It is the follow up that matters.  Remember the WMD?  Or forget that already?

 
 
 
Perrie Halpern R.A.
Professor Expert
3.2  Perrie Halpern R.A.  replied to  Sean Treacy @3    4 years ago

Sean,

Where did you get your information from? There is nothing I can find that will agree with you.

 
 
 
Sean Treacy
Professor Principal
3.2.1  Sean Treacy  replied to  Perrie Halpern R.A. @3.2    4 years ago

The New York Times today:

Now some researchers are wrestling with a hopeful possibility. In interviews with The New York Times, more than a dozen scientists said that the threshold is likely to be much lower: just 50 percent, perhaps even less. If that’s true, then it may be possible to turn back the coronavirus more quickly than once thought.

 
 
 
Tessylo
Professor Principal
3.2.2  seeder  Tessylo  replied to  Sean Treacy @3.2.1    4 years ago

Source?  Citation?  

Nonsense . . . . 

 
 
 
Sean Treacy
Professor Principal
3.2.3  Sean Treacy  replied to  Tessylo @3.2.2    4 years ago

Today's New York Times is the source. Did you miss that? 

 
 
 
Tessylo
Professor Principal
3.2.4  seeder  Tessylo  replied to  Sean Treacy @3.2.3    4 years ago

Just because you say it's from the New York Times today, doesn't mean diddly without a link/citation.

Did you miss that?

 
 
 
Perrie Halpern R.A.
Professor Expert
3.2.5  Perrie Halpern R.A.  replied to  Sean Treacy @3.2.3    4 years ago

I found it and I have to say, that it says a lot of nothing. It is not written by a science journalist and he doesn't say who the scientists are, or where the studies are were done. 

Read it here:

And then read this:

 
 
 
Sean Treacy
Professor Principal
3.2.6  Sean Treacy  replied to  Perrie Halpern R.A. @3.2.5    4 years ago
And then read this:

Why? It has nothing to do with what I wrote.  

 
 
 
Tessylo
Professor Principal
3.3  seeder  Tessylo  replied to  Sean Treacy @3    4 years ago

"This is an outdated article with outdated thinking."

July 27, 2020

 
 
 
bbl-1
Professor Quiet
3.3.1  bbl-1  replied to  Tessylo @3.3    4 years ago

In MAGA land three days is three millennia.  The flotsam never ceases. 

 
 
 
Sean Treacy
Professor Principal
3.3.2  Sean Treacy  replied to  bbl-1 @3.3.1    4 years ago

yes, 3 weeks is a long time in the study of this virus. 

I'm using sources from today. Try and keep abreast of developments. 

 
 
 
Ender
Professor Principal
3.3.3  Ender  replied to  bbl-1 @3.3.1    4 years ago

 Meanwhile studies are showing that even people with mild symptoms are having underlying heart conditions.

Herd immunity my ass.

 
 
 
Sean Treacy
Professor Principal
3.3.4  Sean Treacy  replied to  Ender @3.3.3    4 years ago

Imagine thinking those two things are related

 
 
 
Tessylo
Professor Principal
3.3.5  seeder  Tessylo  replied to  Sean Treacy @3.3.4    4 years ago

They are related.  

 
 
 
Perrie Halpern R.A.
Professor Expert
3.3.6  Perrie Halpern R.A.  replied to  Sean Treacy @3.3.4    4 years ago

They are indeed related:

This concern was addressed in the findings of a new   study   published in JAMA last month, demonstrating that even if you are unaware of having any symptoms after recovery from Covid-19, there is the possibility that the virus may cause heart damage or inflammation that could put you at risk for complications including heart arrhythmias, heart failure and sudden cardiac death. The study looked at 100 patients (median age of just 49) who recently recovered from Covid-19, most of whom were asymptomatic or had just mild symptoms. The researchers, who performed MRI scan of their hearts an average of 2 months after they first were diagnosed with Covid-19, uncovered some concerning findings: 78% of patients had ongoing heart abnormalities and 60 percent had myocarditis, inflammation of the heart muscle. Even more concerning was that the extent of myocarditis was not related to the severity of the initial illness or overall course of the illness.

 
 
 
Sean Treacy
Professor Principal
3.3.7  Sean Treacy  replied to  Perrie Halpern R.A. @3.3.6    4 years ago

That says nothing about herd immunity. I thought that was the topic. 

But by all means, explains how this complication from Covid make herd immunity impossible.

 
 
 
Ender
Professor Principal
3.3.8  Ender  replied to  Sean Treacy @3.3.7    4 years ago

Because honestly I believe with this virus herd immunity is a myth.

People will keep getting infected and then stuck with major health problems down the line.

 
 
 
pat wilson
Professor Participates
3.3.9  pat wilson  replied to  Sean Treacy @3.3.7    4 years ago
how this complication from Covid make herd immunity impossible.

Maybe the fact that some people who've had covid and recovered have been re-infected. That kinda tosses immunity out the window. So you also have to question the efficacy of a vaccine.

 
 
 
Sean Treacy
Professor Principal
3.3.10  Sean Treacy  replied to  Ender @3.3.8    4 years ago
eople will keep getting infected and then stuck with major health problems down the line.

Well if immunity doesn't exist longer than a couple months that's true. But assuming it does or at least limits the severity of future infections, I trust the data that shows the spread of the disease will be limited as local populations exceed 20-30% infection rates. 

For example, NYC will continue to have cases of Covid, but it's highly unlikely it will ever be a "hot spot" again,  as their simply aren't enough available hosts for the explosive growth we've seen in untouched populations..

 
 
 
Ender
Professor Principal
3.3.11  Ender  replied to  Sean Treacy @3.3.10    4 years ago

I have to wonder how people think it would ever be limited to certain people.

It only takes one to infect a lot of others.

 
 
 
Perrie Halpern R.A.
Professor Expert
3.3.12  Perrie Halpern R.A.  replied to  Sean Treacy @3.3.7    4 years ago

It means that even people who get infected and show no signs can end up with widespread damage to their organs. It is not a disease that one can just walk away from. even when it seems that you are unaffected. 

 
 
 
Ender
Professor Principal
3.3.13  Ender  replied to  Perrie Halpern R.A. @3.3.12    4 years ago

Things like that worry me as I have a heart murmur. I would think the last thing I would need would be heart inflammation.

And it is not just the heart that can get damage.

We don't even know what the long term impact is going to be.

Could very well be a lot of people that would need long term healthcare.

 
 
 
sandy-2021492
Professor Expert
3.3.14  sandy-2021492  replied to  Sean Treacy @3.3.7    4 years ago

It means that infection might be a really lousy way to achieve herd immunity.  If achieving immunity via infection rather than vaccination means risking heart damage and death, even when you had mild symptoms, then it's probably not the best route to take.  78% risk of damage to the ticker in people who weren't even that sick with it are odds I don't like.

 
 
 
Tessylo
Professor Principal
3.3.15  seeder  Tessylo  replied to  Sean Treacy @3.3.7    4 years ago

It's tiresome putting the reasons why herd immunity and CO-VID 19 will not work.  That puts millions of people at risk.  That makes millions of people DEAD.  

 
 
 
bbl-1
Professor Quiet
4  bbl-1    4 years ago

Actually 'herd immunity' does have its merits.  Example;  it was calculated that a certain per cent of the soldiers taking part in The Normandy Invasion would be casualties.  Don't know what that has to with COVID but I am sure some 'fringe occupants' will try that on for size.

Trouble with the 'herd immunity' concept is always the lack of volunteers. 

 
 
 
devangelical
Professor Principal
5  devangelical    4 years ago

if you don’t care how many people die

meh, I guess it depends on which people...

 
 
 
igknorantzrulz
PhD Quiet
5.1  igknorantzrulz  replied to  devangelical @5    4 years ago

the 'right' 

people

 
 
 
Bob Nelson
Professor Guide
5.2  Bob Nelson  replied to  devangelical @5    4 years ago

The ultra-rich will always have the very best of care, so they can take any risks.

And nobody cares about the poor...

 
 
 
Account Deleted
Freshman Silent
6  Account Deleted    4 years ago

Modeling this is not difficult. You can do it with pencil, paper and a calculator. Easier with a spread sheet. The problem is you need the following data.

1. The present infection rate - how many have had Covid.

2. How many have died.

Number 2 is the easiest one though you have to decide if Covid was the cause of death. Someone who dies in an auto accident and happens to have Covid. Don't know. Did the illness contribute to the accident - should you count it?

Number 1 is the problem. The "cases" you see posted do not recognize those who actually contracted the disease but either had no symptoms or thought they had allergies etc. and did not bother to be tested.

We have estimates  from some antibody testing - somewhere from 5 to 10 times as many people have had Covid than those who get tested and are positive. (Sweden, US CDC)

To have a better idea, we would need to do random testing for antibodies - maybe break the US into 4 or 5 regions and randomly test 2,000 in each region.

Death rate estimates from China, South Korea, and US CDC range from .004 to .007

So if present infection rates (people how have been infected in the US) are somewhere between 8% to 16% most models will show  between 500,000 and 1,000,000 deaths long before you get to 70%.

Collect better data, get better models.

 
 
 
Buzz of the Orient
Professor Expert
7  Buzz of the Orient    4 years ago

I love the "herd Immunity" logic.  If 100% of Americans contract the virus, America won't need to indicate increasing numbers any more, except numbers of deaths.  America can regain its reputation as a world leader, it can LEAD THE WORLD with the least number of new cases.  LOL

 
 
 
Account Deleted
Freshman Silent
8  Account Deleted    4 years ago

Gee - I don't really understand this herd thing.

First scenario - say I'm in a big room with 99 other people. 98 people have had Covid and are recovered. Number 99, me, has never been exposed. Number 100 is infectious.

Second scenario - I'm in a big room with 99 other people. 99 people have never been exposed to the virus  and are well (that includes me). Number 100 is infectious.

How exactly will herd immunity help me?

 
 

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